Jesse Isaacman-Beck, PhD, is the Director of the Division of Artificial Intelligence Policy and Strategy at the U.S. Department of Health and Human Services (HHS). In this role, he works to maximize Departmental effectiveness through emerging technology and to catalyze innovation to advance the health and well-being of all Americans. Working closely with HHS’s Chief Information, AI, and Data Officers, he has played a central role in establishing HHS’s AI governance framework, developing AI strategy across administrations, and executing federal AI and data policy directives. His work has included launching the HHS AI Governance Board, shaping HHS AI use case oversight, modernizing HHS’s IT, AI, and data policy, and leading the creation of HHS’s first public Data Inventory. Previously, Dr. Isaacman-Beck served in the NIH Office of Science Policy and as an AAAS Science & Technology Policy Fellow. He holds a PhD and trained as a neuroscientist at the University of Pennsylvania and Stanford University.